Endocrine Abstracts

Tumour necrosis factor-α (TNF-α) impairs liver function and contributes to the pathogenesis of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (DM-2) with different trophological status.Purpose: To assess the relationship between the level of TNF-α and indices of carbohydrate metabolism in patients with NAFLD and its combination with DM-2 with different trophological status.Methods:...

There is a need in study of resistin (R) role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) against the background of metabolic disorders.Aim: To assess the relationship between R and indexes of enzyme and pigment metabolism in patients (pts) with NAFLD combined with diabetes mellitus (DM) type 2 and obesity (Ob).Methods: Fifty pts with NAFLD in combination with subcompensated DM (HbA1c 8.3±1.7%) and Ob (BMI&...